The clinical spectrum of antiropositive cutaneous neonatal lupus erythematosus. Lupus eritematoso sistemico bermudez marrero acta medica del. Neonatal lupus erythematosus is an infrequent disease seen in newborns. Pediatric systemic lupus erythematosus, report of a case cinthia claros a. Systemic lupus erythematosus sle is an autoimmune disease in which organs, tissues and cells are damaged by immune complexes. O lupus eritematoso sistemico pode apresentar inumeras lesoes cutaneas. Ultraviolet radiation is the environmental factor most linked to lupus, and causes exacerbation in 70% of patients to increase apoptosis of keratinocytes and other cells or by altering the dna and intracellular proteins so they become antigenic. Fisiopatologia del lupus eritematoso sistemico elsevier. Neonatal lupus erythematosus multisystem involvement congenital heart block autoantibodies a bstract neonatal lupus erythematosus is an infrequent disease seen in newborns. Las principales manifestaciones clinicas son dermatologicas y cardiacas, pudiendo ademas presentar manifestaciones hepaticas, hematologicas. Citescore values are based on citation counts in a given year e.
Lupus eritematoso disseminado wikipedia, a enciclopedia livre. Cutaneous involvement and congenital heart block chb are the most common affections, although it may involve multiple organs like the liver, lungs, blood, nervous or digestive systems. Rituximab therapy for multisystem autoimmune diseases in pediatric patients. Manifestaciones mucocutaneas exantema malar lupus pernio fotosensibilidad livedo reticularis lupus discoide purpura lupus subagudo alopecia eritema palmar paniculitis eritema generalizado vasculitis. Francisco xavier olmosgarcia luz maria suarezlarios. Lupus eritematoso sistemico bermudez marrero acta medica. Lupus eritematoso generalizado, autoanticuerpos, inmunopatogenia. It is caused by transplacental maternal autoantibody passage. Lupus eritematoso sistemico julia garciaconsuegra molina 9 manifestaciones clinicas sindrome constitucional.
Etiology and pathogenesis of systemic lupus erythematosus. Come accade nelle altre malattie autoimmuni, il sistema immunitario produce autoanticorpi che, invece di proteggere il corpo da virus, batteri e agenti estranei, aggrediscono cellule e componenti del corpo stesso, causando. Request pdf on mar 1, 20, rosa merino munoz and others published lupus eritematoso sistemico find, read and cite all the research you need on researchgate. Protocolo clinico e diretrizes terapeuticas lupus eritematoso.